Ovalbumine  Antigen -Specifieke Activatie van menselijke T-cel -receptor  lijkt sterk

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Chimère  antigeen  receptor  T-cellen (CAR-T-cellen) de toekomst in immunotherapie voor auto-immuunziekten?

Doelstelling:  CAR-T-celtherapie heeft een revolutie teweeggebracht in de behandeling van oncologische ziekten en recentelijk zijn mogelijke toepassingen bij auto-immuunziekten beschreven. De beoordeling heeft tot doel de beschikbare gegevens over de behandeling met CAR-T-cellen te integreren, met de nadruk op auto-immuunziekten, om de therapeutische vooruitgang en hun mogelijke toekomstige klinische toepasbaarheid bij auto-immuniteit te bepalen.

Materialen en methoden:  Er is gezocht in PubMed met de trefwoorden “Chimeric Antigen Receptor” en “CART cell”. De relevante documenten werden geselecteerd en de informatie werd kritisch bekeken.

Resultaten:  Bij de behandeling van auto-immuunziekten zijn in preklinische modellen drie verschillende cellulaire strategieën gebruikt, waaronder chimere antigeenreceptor T-cellen, chimere auto-antilichaamreceptor T-cellen en chimere antigeenreceptor in regulerende T-lymfocyten . Alle drie soorten therapie zijn effectief geweest. De mogelijke nadelige effecten daarin, het cytokine-afgiftesyndroom, cellulaire toxiciteit en neurotoxiciteit moeten altijd in gedachten worden gehouden.

Conclusies:  Hoewel er nog geen informatie over mensen beschikbaar is, laten preklinische modellen van CAR-T-cellen bij de behandeling van auto-immuunziekten veelbelovende resultaten zien, zodat ze in de toekomst een nuttige en effectieve therapie kunnen worden bij de behandeling van deze pathologieën.

Ovalbumine  Antigen -Specifieke Activatie van menselijke T-cel  -receptor  lijkt sterk op Oplosbare Antibody Stimulatieter onthuld door BOOST fosfotyrosine Proteomics

Activering van de T-celreceptor (TCR) leidt tot een netwerk van vroege signalering, voornamelijk georkestreerd door tyrosinefosforylering in T-cellen. De TCR wordt gewoonlijk geactiveerd met behulp van oplosbare anti-TCR-antilichamen, maar deze benadering is niet antigeenspecifiek. Als alternatief wordt aangenomen dat het activeren van de TCR met behulp van specifieke antigenen met een reeks bindingsaffiniteiten in de vorm van een peptide-major histocompatibiliteitscomplex (pMHC) meer fysiologisch is. Vanwege het ontbreken van grootschalige fosfotyrosine (pTyr) proteomische onderzoeken die anti-TCR-antilichamen en pMHC rechtstreeks vergelijken, blijft een uitgebreide definitie van deze geactiveerde toestanden echter raadselachtig.

Opheldering van het tyrosinefosfoproteoom met behulp van kwantitatieve pTyr-proteomics maakt een beter begrip mogelijk van de unieke kenmerken van deze activerende middelen en de rol van ligandbindingsaffiniteit op signalering. Hier passen we de current opgerichte breedspectrumoptimalisatie van selectieve triggering (BOOST) toe om verstoringen in tyrosinefosforylering van menselijke TCR te onderzoeken, veroorzaakt door anti-TCR-antilichamen en pMHC. Onze gegevens laten zien dat pMHC-activering met hoge affiniteit ovalbumine (OVA) van de menselijke TCR een grotendeels vergelijkbare, zij het mogelijk sterkere, pTyr-gemedieerdesignaalregulerende as vergeleken met het anti-TCR-antilichaam. De signaleringsoutput die resulteert uit OVA pMHC-varianten correleert goed met hun zwakkere affiniteiten, waardoor affiniteit-afstembare controle van de signaalsterkte mogelijk is. Gezamenlijk bieden we een raamwerk voor het toepassen van BOOST om pTyr-gemedieerde signaalroutes van menselijke T-cellen te vergelijken die op een antigeenonafhankelijke en antigeenspecifieke manier zijn geactiveerd.

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Recombinant Human ITGB1 Protein, His, E.coli-20ug

QP12462-HIS-20ug 20ug
EUR 201

Recombinant Human ITGB1 Protein, His, E.coli-2ug

QP12462-HIS-2ug 2ug
EUR 155

Recombinant Human ITGB1 Protein, His, E.coli-5ug

QP12462-HIS-5ug 5ug
EUR 155

Recombinant Human ITGB1 Protein, His, E.coli-1mg

QP12462-HIS-EC-1mg 1mg
EUR 2757

ITGB1 protein (His tag)

80R-3617 100 ug
EUR 327
Description: Purified recombinant ITGB1 protein (His tag)

Human Integrin Beta 1 (ITGb1) ELISA Kit

DLR-ITGb1-Hu-48T 48T
EUR 498
  • Should the Human Integrin Beta 1 (ITGb1) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Human Integrin Beta 1 (ITGb1) in samples from tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Human Integrin Beta 1 (ITGb1) ELISA Kit

DLR-ITGb1-Hu-96T 96T
EUR 647
  • Should the Human Integrin Beta 1 (ITGb1) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Human Integrin Beta 1 (ITGb1) in samples from tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Human Integrin Beta 1 (ITGb1) ELISA Kit

RDR-ITGb1-Hu-48Tests 48 Tests
EUR 522

Human Integrin Beta 1 (ITGb1) ELISA Kit

RDR-ITGb1-Hu-96Tests 96 Tests
EUR 724

Human Integrin Beta 1 (ITGb1) ELISA Kit

RD-ITGb1-Hu-48Tests 48 Tests
EUR 500

Human Integrin Beta 1 (ITGb1) ELISA Kit

RD-ITGb1-Hu-96Tests 96 Tests
EUR 692

XMIR-21 RNA oligo miRNA-21-5p with Xmotif

XMIR-21 10 rxn
EUR 438
  • Category: Exosome

Recombinant Human ITGB1 Protein, His, Insect-1mg

QP12462-HIS-INSECT-1mg 1mg
EUR 5251

AXMIR-21 RNA oligo anti-miRNA-21-5p with Xmotif

AXMIR-21 10 reactions
EUR 438
  • Category: Exosome

Recombinant (E.coli) Human CD40 (aa: 21-193, His Tag, >95% Pure)

HCD4015-N-10 10 ug
EUR 286

Recombinant (E.Coli, His-tag) Human Syndecan-4, His-tag

RP-993 10 ug
EUR 225

Recombinant (E.coli) Rat CD40 (aa: 21-193, His Tag, >95% Pure)

RCD4015-N-10 10 ug
EUR 213

FGF-21 Fibroblast Growth Factor-21 Human Recombinant Protein, His Tag

PROTQ9NSA1 Regular: 50ug
EUR 317
Description: Fibroblast Growth Factor -21 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 202 amino acids (29-209) and having a molecular mass of 21.6 kDa (molecular weight on SDS-PAGE will appear higher). ;The FGF-21 is fused to a 20 amino acid His Tag at N-terminus and purified by proprietary chromatographic techniques.

XMIRXpress lentivector miRNA-21-5p with Xmotif

XMIRXP-21 10 ug
EUR 677
  • Category: Exosome

Recombinant Human Fibroblast Growth Factor-21, His Tag

7-00385 10µg Ask for price

Recombinant Human Fibroblast Growth Factor-21, His Tag

7-00386 50µg Ask for price

Recombinant Human Fibroblast Growth Factor-21, His Tag

7-00387 1mg Ask for price

Recombinant (E.Coli, His-tag) Human HTRA2

RP-413 10 ug
EUR 225

Recombinant (E.Coli, His-tag) Human STAT1

RP-722 10 ug
EUR 286

Recombinant (E.Coli, His-tag) Human S100b

RP-774 10 ug
EUR 286

Recombinant (E.Coli, His-tag) Human Osteocrin

RP-868 10 ug
EUR 286

Recombinant (E.Coli, His-tag) Human CD29

RP-915 2 ug
EUR 347

Recombinant (E.Coli, His-tag) Human Geminin

RP-989 5 ug
EUR 164

FGF-21 Fibroblast Growth Factor-21 Mouse Recombinant Protein, His Tag

PROTQ9JJN1-1 Regular: 10ug
EUR 317
Description: Fibroblast Growth Factor -21 Mouse Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 192 amino acids and having a molecular mass of 21.2 kDa. The amino acid sequence of the recombinant human FGF21 is 100% homologous to the amino acid sequence of the Mouse FGF21 without signal sequence and contains 10 a.a. His tag at N-terminal.;The FGF-21 is purified by proprietary chromatographic techniques.

Recombinant (E.Coli, His-tag) Human Ubiquitin Conjugating enzyme 7, His-tag

RP-425 10 ug
EUR 225

Human ITGA1&ITGB1 Heterodimer Protein (Phe 29-Pro 1141 (ITGA1)&Gln 21-Asp 728 (ITGB1))

VAng-1839Lsx-100g 100 µg
EUR 1178
Description: Human ITGA1&ITGB1 Heterodimer protein, expressed in human 293 cells. (Uniprot ID: P56199-1 (ITGA1)&P05556-1 (ITGB1))

Human ITGA1&ITGB1 Heterodimer Protein (Phe 29-Pro 1141 (ITGA1)&Gln 21-Asp 728 (ITGB1))

VAng-1839Lsx-1mg 1 mg
EUR 7969
Description: Human ITGA1&ITGB1 Heterodimer protein, expressed in human 293 cells. (Uniprot ID: P56199-1 (ITGA1)&P05556-1 (ITGB1))

Human ITGA10&ITGB1 Heterodimer Protein (Phe 23-Ser 1122 (ITGA10)&Gln 21-Asp 728 (ITGB1))

VAng-1840Lsx-100g 100 µg
EUR 1178
Description: Human ITGA10&ITGB1 Heterodimer protein, expressed in human 293 cells. (Uniprot ID: O75578-1 (ITGA10)&P05556-1 (ITGB1))

Human ITGA10&ITGB1 Heterodimer Protein (Phe 23-Ser 1122 (ITGA10)&Gln 21-Asp 728 (ITGB1))

VAng-1840Lsx-1mg 1 mg
EUR 7969
Description: Human ITGA10&ITGB1 Heterodimer protein, expressed in human 293 cells. (Uniprot ID: O75578-1 (ITGA10)&P05556-1 (ITGB1))

Human ITGA11&ITGB1 Heterodimer Protein (Phe 23-Ser 1122 (ITGA10)&Gln 21-Asp 728 (ITGB1))

VAng-1841Lsx-100g 100 µg
EUR 1178
Description: Human ITGA11&ITGB1 Heterodimer protein, expressed in human 293 cells. (Uniprot ID: Q9UKX5-1 (L524R) (ITGA11)&P05556-1 (ITGB1))

Human ITGA11&ITGB1 Heterodimer Protein (Phe 23-Ser 1122 (ITGA10)&Gln 21-Asp 728 (ITGB1))

VAng-1841Lsx-1mg 1 mg
EUR 7969
Description: Human ITGA11&ITGB1 Heterodimer protein, expressed in human 293 cells. (Uniprot ID: Q9UKX5-1 (L524R) (ITGA11)&P05556-1 (ITGB1))

Human ITGA4&ITGB1 Heterodimer Protein (Tyr 34-Thr 977 (ITGA4)&Gln 21-Asp 728 (ITGB1))

VAng-1842Lsx-100g 100 µg
EUR 1178
Description: Human ITGA4&ITGB1 Heterodimer protein, expressed in human 293 cells. (Uniprot ID: P13612-1 (ITGA4)&P05556-1 (ITGB1))

Human ITGA4&ITGB1 Heterodimer Protein (Tyr 34-Thr 977 (ITGA4)&Gln 21-Asp 728 (ITGB1))

VAng-1842Lsx-1mg 1 mg
EUR 7969
Description: Human ITGA4&ITGB1 Heterodimer protein, expressed in human 293 cells. (Uniprot ID: P13612-1 (ITGA4)&P05556-1 (ITGB1))

Human ITGA5&ITGB1 Heterodimer Protein (Phe 42-Tyr 995 (ITGA5)&Gln 21-Asp 728 (ITGB1))

VAng-1844Lsx-100g 100 µg
EUR 1178
Description: Human ITGA5&ITGB1 Heterodimer protein, expressed in human 293 cells. (Uniprot ID: P08648-1 (ITGA5)&P05556-1 (ITGB1))

Human ITGA5&ITGB1 Heterodimer Protein (Phe 42-Tyr 995 (ITGA5)&Gln 21-Asp 728 (ITGB1))

VAng-1844Lsx-1mg 1 mg
EUR 7969
Description: Human ITGA5&ITGB1 Heterodimer protein, expressed in human 293 cells. (Uniprot ID: P08648-1 (ITGA5)&P05556-1 (ITGB1))

Human ITGA7X2B&ITGB1 Heterodimer Protein (Phe 34-Trp 1038 (ITGA7X2B)&Gln 21-Asp 728 (ITGB1))

VAng-1846Lsx-100g 100 µg
EUR 1178
Description: Human ITGA7X2B&ITGB1 Heterodimer protein, expressed in human 293 cells. (Uniprot ID: Q13683-7 (ITGA7X2B)&P05556-1 (ITGB1))

Human ITGA7X2B&ITGB1 Heterodimer Protein (Phe 34-Trp 1038 (ITGA7X2B)&Gln 21-Asp 728 (ITGB1))

VAng-1846Lsx-1mg 1 mg
EUR 7969
Description: Human ITGA7X2B&ITGB1 Heterodimer protein, expressed in human 293 cells. (Uniprot ID: Q13683-7 (ITGA7X2B)&P05556-1 (ITGB1))

Human ITGA8&ITGB1 Heterodimer Protein (Phe 39-Leu 1012 (ITGA8)&Gln 21-Asp 728 (ITGB1))

VAng-1847Lsx-100g 100 µg
EUR 1178
Description: Human ITGA8&ITGB1 Heterodimer protein, expressed in human 293 cells. (Uniprot ID: P53708-1 (ITGA8)&P05556-1 (ITGB1))

Human ITGA8&ITGB1 Heterodimer Protein (Phe 39-Leu 1012 (ITGA8)&Gln 21-Asp 728 (ITGB1))

VAng-1847Lsx-1mg 1 mg
EUR 7969
Description: Human ITGA8&ITGB1 Heterodimer protein, expressed in human 293 cells. (Uniprot ID: P53708-1 (ITGA8)&P05556-1 (ITGB1))

Human ITGA9&ITGB1 Heterodimer Protein (Phe 39-Leu 1012 (ITGA8)&Gln 21-Asp 728 (ITGB1))

VAng-1848Lsx-100g 100 µg
EUR 1178
Description: Human ITGA9&ITGB1 Heterodimer protein, expressed in human 293 cells. (Uniprot ID: Q13797-1 (ITGA9)&P05556-1 (ITGB1))

Human ITGA9&ITGB1 Heterodimer Protein (Phe 39-Leu 1012 (ITGA8)&Gln 21-Asp 728 (ITGB1))

VAng-1848Lsx-1mg 1 mg
EUR 7969
Description: Human ITGA9&ITGB1 Heterodimer protein, expressed in human 293 cells. (Uniprot ID: Q13797-1 (ITGA9)&P05556-1 (ITGB1))

Human ITGAV&ITGB1 Heterodimer Protein (Phe 31-Val 992 (ITGAV)&Gln 21-Asp 728 (ITGB1))

VAng-1852Lsx-100g 100 µg
EUR 1178
Description: Human ITGAV&ITGB1 Heterodimer protein, expressed in human 293 cells. (Uniprot ID: NP_002201.1 (ITGAV)&P05556-1 (ITGB1))

Human ITGAV&ITGB1 Heterodimer Protein (Phe 31-Val 992 (ITGAV)&Gln 21-Asp 728 (ITGB1))

VAng-1852Lsx-200g 200 µg
EUR 7969
Description: Human ITGAV&ITGB1 Heterodimer protein, expressed in human 293 cells. (Uniprot ID: NP_002201.1 (ITGAV)&P05556-1 (ITGB1))

Recombinant E.coli LACTB Protein, His, E.coli-20ug

QP12522-HIS-20ug 20ug
EUR 201

Recombinant E.coli LACTB Protein, His, E.coli-5ug

QP12522-HIS-5ug 5ug
EUR 155

Histidine-tag (poly-His/Hisx6) Protein (His-tag-fusion protein) ELISA Kit, 96 tests, Quantitative

800-440-HIS 1 kit
EUR 895

Recombinant Mouse Fibroblast Growth Factor-21, His Tag

7-00391 2µg Ask for price

Recombinant Mouse Fibroblast Growth Factor-21, His Tag

7-00392 10µg Ask for price

Recombinant Mouse Fibroblast Growth Factor-21, His Tag

7-00393 1mg Ask for price

Recombinant (E.Coli) Human Eotaxin (CCL11), His-tag

RP-1045 5 ug
EUR 164

Recombinant (E.Coli, His-tag) Human AminoAcylase-1

RP-382 10 ug
EUR 286

Recombinant (E.Coli, His-tag) Human Paraoxonase-1

RP-385 10 ug
EUR 286

Recombinant (E.Coli, His-tag) Human Paraoxonase-2

RP-386 10 ug
EUR 286

Recombinant (E.Coli, His-tag) )Human Chorionic Gonadotropin

RP-599 10 ug
EUR 225

Recombinant (E.Coli, His-tag) Human Beta-Trace

RP-783 10 ug
EUR 286

Recombinant (E.Coli, His-tag) Human L-Selectin

RP-835 10 ug
EUR 286

Recombinant (E.Coli, His-tag) Human P-Selectin

RP-836 10 ug
EUR 286

Recombinant (E.Coli, His-tag) Human Annexin 7

RP-890 10 ug
EUR 286

Recombinant (E.Coli, His-tag) Human Annexin 9

RP-891 10 ug
EUR 286

Recombinant (E.Coli, His-tag) Human Ephrin A1

RP-936 2 ug
EUR 347

Recombinant (E.Coli, His-tag) Human Ephrin B1

RP-937 2 ug
EUR 347

Recombinant (E.Coli, His-tag) Human Ephrin B3

RP-938 2 ug
EUR 347

Recombinant (E.Coli, His-tag) Human Fyn-p59

RP-946 2 ug
EUR 347

Recombinant (E.Coli, His-tag) Human Melanoma (gp100)

RP-949 2 ug
EUR 347

Recombinant (E.Coli, His-tag) Human Mammaglobin-A

RP-952 2 ug
EUR 347

Recombinant (E.Coli, His-tag) Human Synaptobrevin-1

RP-987 20 ug
EUR 164

Recombinant (E.Coli, His-tag) Human Synaptobrevin-2

RP-988 5 ug
EUR 164

Biotinylated Human ITGA4&ITGB1 Heterodimer Protein (Tyr 34-Thr 977 (ITGA4)&Gln 21-Asp 728 (ITGB1))

VAng-1621Lsx-200g 200 µg
EUR 3844
Description: Biotinylated Human ITGA4&ITGB1 Heterodimer protein, expressed in human 293 cells. (Uniprot ID: P13612-1 (ITGA4)&P05556-1 (ITGB1))

Biotinylated Human ITGA4&ITGB1 Heterodimer Protein (Tyr 34-Thr 977 (ITGA4)&Gln 21-Asp 728 (ITGB1))

VAng-1621Lsx-25g 25 µg
EUR 1013
Description: Biotinylated Human ITGA4&ITGB1 Heterodimer protein, expressed in human 293 cells. (Uniprot ID: P13612-1 (ITGA4)&P05556-1 (ITGB1))

Biotinylated Human ITGA5&ITGB1 Heterodimer Protein (Phe 42-Tyr 995 (ITGA5)&Gln 21-Asp 728 (ITGB1))

VAng-1623Lsx-200g 200 µg
EUR 3844
Description: Biotinylated Human ITGA5&ITGB1 Heterodimer protein, expressed in human 293 cells. (Uniprot ID: P08648-1 (ITGA5)&P05556-1 (ITGB1))

Biotinylated Human ITGA5&ITGB1 Heterodimer Protein (Phe 42-Tyr 995 (ITGA5)&Gln 21-Asp 728 (ITGB1))

VAng-1623Lsx-25g 25 µg
EUR 1013
Description: Biotinylated Human ITGA5&ITGB1 Heterodimer protein, expressed in human 293 cells. (Uniprot ID: P08648-1 (ITGA5)&P05556-1 (ITGB1))

Biotinylated Human ITGA8&ITGB1 Heterodimer Protein (Phe 39-Leu 1012 (ITGA8)&Gln 21-Asp 728 (ITGB1))

VAng-1624Lsx-200g 200 µg
EUR 3844
Description: Biotinylated Human ITGA8&ITGB1 Heterodimer protein, expressed in human 293 cells. (Uniprot ID: P53708-1 (ITGA8)&P05556-1 (ITGB1))

Biotinylated Human ITGA8&ITGB1 Heterodimer Protein (Phe 39-Leu 1012 (ITGA8)&Gln 21-Asp 728 (ITGB1))

VAng-1624Lsx-25g 25 µg
EUR 1013
Description: Biotinylated Human ITGA8&ITGB1 Heterodimer protein, expressed in human 293 cells. (Uniprot ID: P53708-1 (ITGA8)&P05556-1 (ITGB1))

Biotinylated Human ITGAV&ITGB1 Heterodimer Protein (Phe 31-Val 992 (ITGAV)&Gln 21-Asp 728 (ITGB1))

VAng-1625Lsx-200g 200 µg
EUR 3844
Description: Biotinylated Human ITGAV&ITGB1 Heterodimer protein, expressed in human 293 cells. (Uniprot ID: NP_002201.1 (ITGAV)&P05556-1 (ITGB1))

Biotinylated Human ITGAV&ITGB1 Heterodimer Protein (Phe 31-Val 992 (ITGAV)&Gln 21-Asp 728 (ITGB1))

VAng-1625Lsx-25g 25 µg
EUR 1013
Description: Biotinylated Human ITGAV&ITGB1 Heterodimer protein, expressed in human 293 cells. (Uniprot ID: NP_002201.1 (ITGAV)&P05556-1 (ITGB1))

Human ITGA6&ITGB1 Heterodimer Protein (Phe 24-Gly 1012 (ITGA6) and Gln 21-Asp 728 (ITGB1))

VAng-1845Lsx-100g 100 µg
EUR 1178
Description: Human ITGA6&ITGB1 Heterodimer protein, expressed in human 293 cells. (Uniprot ID: P23229-2 (ITGA6)&P05556-1 (ITGB1))

Human ITGA6&ITGB1 Heterodimer Protein (Phe 24-Gly 1012 (ITGA6) and Gln 21-Asp 728 (ITGB1))

VAng-1845Lsx-1mg 1 mg
EUR 7969
Description: Human ITGA6&ITGB1 Heterodimer protein, expressed in human 293 cells. (Uniprot ID: P23229-2 (ITGA6)&P05556-1 (ITGB1))

Recombinant Human EDA2R Protein, His, E.coli-10ug

QP11743-HIS-10ug 10ug
EUR 201

Recombinant Human EDA2R Protein, His, E.coli-20ug

QP11743-HIS-20ug 20ug
EUR 201

Recombinant Human EDA2R Protein, His, E.coli-2ug

QP11743-HIS-2ug 2ug
EUR 155

Recombinant Human EDA2R Protein, His, E.coli-5ug

QP11743-HIS-5ug 5ug
EUR 155

Recombinant Human EDAR Protein, His, E.coli-10ug

QP11744-HIS-10ug 10ug
EUR 201

Recombinant Human EDAR Protein, His, E.coli-20ug

QP11744-HIS-20ug 20ug
EUR 201

Recombinant Human EDAR Protein, His, E.coli-2ug

QP11744-HIS-2ug 2ug
EUR 155

Recombinant Human EDAR Protein, His, E.coli-5ug

QP11744-HIS-5ug 5ug
EUR 155

Recombinant Human EDN2 Protein, His, E.coli-1mg

QP11746-HIS-1mg 1mg
EUR 2757

Recombinant Human EDN2 Protein, His, E.coli-20ug

QP11746-HIS-20ug 20ug
EUR 201

Recombinant Human EDN2 Protein, His, E.coli-5ug

QP11746-HIS-5ug 5ug
EUR 155

Recombinant Human EDN3 Protein, His, E.coli-1ug

QP11747-HIS-1ug 1ug
EUR 155

Recombinant Human EDN3 Protein, His, E.coli-50ug

QP11747-HIS-50ug 50ug
EUR 1261

Recombinant Human EDN3 Protein, His, E.coli-5ug

QP11747-HIS-5ug 5ug
EUR 201

Recombinant Human EFNB3 Protein, His, E.coli-10ug

QP11756-HIS-10ug 10ug
EUR 201

Recombinant Human EFNB3 Protein, His, E.coli-20ug

QP11756-HIS-20ug 20ug
EUR 201

Recombinant Human EFNB3 Protein, His, E.coli-2ug

QP11756-HIS-2ug 2ug
EUR 155

Recombinant Human EFNB3 Protein, His, E.coli-5ug

QP11756-HIS-5ug 5ug
EUR 155

Recombinant Human En Protein, His, E.coli-100ug

QP11784-HIS-100ug 100ug
EUR 1261

Recombinant Human ERCC1 Protein, His, E.coli-1mg

QP11805-HIS-1mg 1mg
EUR 5251

Recombinant Human ESM1 Protein, His, E.coli-10ug

QP11810-HIS-10ug 10ug
EUR 201

Recombinant Human ESM1 Protein, His, E.coli-20ug

QP11810-HIS-20ug 20ug
EUR 201

Recombinant Human ESM1 Protein, His, E.coli-2ug

QP11810-HIS-2ug 2ug
EUR 155

Recombinant Human ESM1 Protein, His, E.coli-5ug

QP11810-HIS-5ug 5ug
EUR 155

Recombinant Human FABP3 Protein, His, E.coli-25ug

QP11835-HIS-25ug 25ug
EUR 201

Recombinant Human FABP4 Protein, His, E.coli-1mg

QP11836-HIS-1mg 1mg
EUR 2558

Recombinant Human FABP4 Protein, His, E.coli-25ug

QP11836-HIS-25ug 25ug
EUR 201

Recombinant Human FABP4 Protein, His, E.coli-5ug

QP11836-HIS-5ug 5ug
EUR 155

Recombinant Human FCGR3A Protein, His, E.coli-10ug

QP11860-HIS-10ug 10ug
EUR 201

Recombinant Human FCGR3A Protein, His, E.coli-20ug

QP11860-HIS-20ug 20ug
EUR 201

Recombinant Human FCGR3A Protein, His, E.coli-2ug

QP11860-HIS-2ug 2ug
EUR 155

Recombinant Human FCGR3A Protein, His, E.coli-5ug

QP11860-HIS-5ug 5ug
EUR 155

Recombinant Human FOLR1 Protein, His, E.coli-1mg

QP11896-HIS-1mg 1mg
EUR 2757

Recombinant Human FOLR1 Protein, His, E.coli-1ug

QP11896-HIS-1ug 1ug
EUR 155

Recombinant Human FOLR1 Protein, His, E.coli-20ug

QP11896-HIS-20ug 20ug
EUR 201

Recombinant Human FOLR1 Protein, His, E.coli-50ug

QP11896-HIS-50ug 50ug
EUR 1261

Recombinant Human GDA Protein, His, E.coli-1mg

QP11946-HIS-1mg 1mg
EUR 2757

Recombinant Human GDA Protein, His, E.coli-20ug

QP11946-HIS-20ug 20ug
EUR 201

Recombinant Human GFRA3 Protein, His, E.coli-1mg

QP11959-HIS-1mg 1mg
EUR 2757

Recombinant Human GFRA3 Protein, His, E.coli-1ug

QP11959-HIS-1ug 1ug
EUR 155

Recombinant Human GFRA3 Protein, His, E.coli-20ug

QP11959-HIS-20ug 20ug
EUR 201

Recombinant Human GFRA3 Protein, His, E.coli-50ug

QP11959-HIS-50ug 50ug
EUR 1261

Recombinant Human GPNMB Protein, His, E.coli-20ug

QP12041-HIS-20ug 20ug
EUR 201

Recombinant Human GPNMB Protein, His, E.coli-5ug

QP12041-HIS-5ug 5ug
EUR 155

Recombinant Human GZMH Protein, His, E.coli-100ug

QP12072-HIS-0.1mg 100ug
EUR 1261

Recombinant Human GZMK Protein, His, E.coli-10ug

QP12073-HIS-10ug 10ug
EUR 201

Recombinant Human GZMK Protein, His, E.coli-20ug

QP12073-HIS-20ug 20ug
EUR 201

Recombinant Human GZMK Protein, His, E.coli-2ug

QP12073-HIS-2ug 2ug
EUR 155

Recombinant Human GZMK Protein, His, E.coli-5ug

QP12073-HIS-5ug 5ug
EUR 155

Recombinant Human HAVCR1 Protein, His, E.coli-10ug

QP12115-HIS-10ug 10ug
EUR 201

Recombinant Human HAVCR1 Protein, His, E.coli-20ug

QP12115-HIS-20ug 20ug
EUR 201

Recombinant Human HAVCR1 Protein, His, E.coli-2ug

QP12115-HIS-2ug 2ug
EUR 155

Recombinant Human HAVCR1 Protein, His, E.coli-5ug

QP12115-HIS-5ug 5ug
EUR 155

Recombinant Human Hemopexin Protein, His, E.coli-1mg

QP12215-HIS-1mg 1mg
EUR 2757

Recombinant Human Hemopexin Protein, His, E.coli-20ug

QP12215-HIS-20ug 20ug
EUR 201

Recombinant Human Hemopexin Protein, His, E.coli-5ug

QP12215-HIS-5ug 5ug
EUR 155

Recombinant Human HEXA Protein, His, E.coli-10ug

QP12224-HIS-10ug 10ug
EUR 201

Recombinant Human HEXA Protein, His, E.coli-20ug

QP12224-HIS-20ug 20ug
EUR 201

Recombinant Human HEXA Protein, His, E.coli-2ug

QP12224-HIS-2ug 2ug
EUR 155

Recombinant Human HEXA Protein, His, E.coli-5ug

QP12224-HIS-5ug 5ug
EUR 155

Recombinant Human HSP27 Protein, His, E.coli-25ug

QP12327-HIS-25ug 25ug
EUR 201

Recombinant Human HSP27 Protein, His, E.coli-5ug

QP12327-HIS-5ug 5ug
EUR 155

Recombinant Human HSPB8 Protein, His, E.coli-1mg

QP12335-HIS-1mg 1mg
EUR 5251

Recombinant Human IGFBP7 Protein, His, E.coli-100ug

QP12384-HIS-100ug 100ug
EUR 1261

Recombinant Human IGFBP7 Protein, His, E.coli-10ug

QP12384-HIS-10ug 10ug
EUR 201

Recombinant Human IGFBP7 Protein, His, E.coli-2ug

QP12384-HIS-2ug 2ug
EUR 155

Recombinant Human IL13RA2 Protein, His, E.coli-10ug

QP12406-HIS-10ug 10ug
EUR 201

Recombinant Human IL13RA2 Protein, His, E.coli-20ug

QP12406-HIS-20ug 20ug
EUR 201

Recombinant Human IL13RA2 Protein, His, E.coli-2ug

QP12406-HIS-2ug 2ug
EUR 155

Recombinant Human IL13RA2 Protein, His, E.coli-5ug

QP12406-HIS-5ug 5ug
EUR 155

Recombinant Human KLF4 Protein, His, E.coli-20ug

QP12498-HIS-20ug 20ug
EUR 201

Recombinant Human KLF4 Protein, His, E.coli-5ug

QP12498-HIS-5ug 5ug
EUR 155

Recombinant Human KLK15 Protein, His, E.coli-1mg

QP12504-HIS-1mg 1mg
EUR 2757

Recombinant Human KLK15 Protein, His, E.coli-1ug

QP12504-HIS-1ug 1ug
EUR 155

Recombinant Human KLK15 Protein, His, E.coli-20ug

QP12504-HIS-20ug 20ug
EUR 201

Recombinant Human KLK15 Protein, His, E.coli-50ug

QP12504-HIS-50ug 50ug
EUR 1261

Recombinant Human KLK2 Protein, His, E.coli-1mg

QP12505-HIS-1mg 1mg
EUR 2757

Recombinant Human KLK2 Protein, His, E.coli-1ug

QP12505-HIS-1ug 1ug
EUR 155

Recombinant Human KLK2 Protein, His, E.coli-20ug

QP12505-HIS-20ug 20ug
EUR 201

Recombinant Human KLK2 Protein, His, E.coli-50ug

QP12505-HIS-50ug 50ug
EUR 1161

Recombinant Human KLK3 Protein, His, E.coli-1mg

QP12506-HIS-1mg 1mg
EUR 2757

Recombinant Human KLK3 Protein, His, E.coli-20ug

QP12506-HIS-20ug 20ug
EUR 201

Recombinant Human KLK3 Protein, His, E.coli-5ug

QP12506-HIS-5ug 5ug
EUR 155

Recombinant Human KLK5 Protein, His, E.coli-100ug

QP12507-HIS-100ug 100ug
EUR 1261

Recombinant Human KLK5 Protein, His, E.coli-1mg

QP12507-HIS-1mg 1mg
EUR 5251

Recombinant Human KLRB1 Protein, His, E.coli-1mg

QP12508-HIS-1mg 1mg
EUR 2757

Recombinant Human KLRB1 Protein, His, E.coli-1ug

QP12508-HIS-1ug 1ug
EUR 155

Recombinant Human KLRB1 Protein, His, E.coli-20ug

QP12508-HIS-20ug 20ug
EUR 201

Recombinant Human KLRB1 Protein, His, E.coli-50ug

QP12508-HIS-50ug 50ug
EUR 1261

Recombinant Human LHRH Protein, His, E.coli-1mg

QP12569-HIS-1mg 1mg
EUR 3655

Recombinant Human LHRH Protein, His, E.coli-20ug

QP12569-HIS-20ug 20ug
EUR 201

Recombinant Human LHRH Protein, His, E.coli-5ug

QP12569-HIS-5ug 5ug
EUR 155

Recombinant Human LIN28 Protein, His, E.coli-10ug

QP12571-HIS-10ug 10ug
EUR 201

Bilaterale anterior cerebrale slagader occlusie na CD19- en BCMA-gerichte chimere  antigeen  receptor  van T-celtherapie voor een patiënt myeloom

Chimere antigeenreceptor T (CAR-T)-celtherapie is een veelbelovende behandeling voor recidiverend/refractair multipel myeloom (RRMM). In ons vorige rapport was CD19- en BCMA-gerichte gelijktijdige toediening van CAR-T geassocieerd met een hoog responspercentage. Hoewel cytokine launch syndrome (CRS) en neurotoxiciteit frequente complicaties zijn na behandeling met CAR-T, wordt een herseninfarct zelden gerapporteerd als een CAR-T-gerelateerde complicatie. We rapporteerden een 73-jarige vrouwelijke MM-patiënt die CD19- en BCMA-gerichte CAR-T ontving voor refractaire ziekte.

Haar ziekte reageerde op CAR-T- therapie, maar ze ontwikkelde neurologische symptomen na CRS. Craniale CT en MRI toonden meerdere herseninfarcten en bilaterale anterieure cerebrale arterie (ACA) occlusie aan. We suggereren dat een ander herseninfarct dan CAR-T-gerelateerde neurotoxiciteit de onderliggende oorzaak is van abnormale neuropsychologische symptomen, en diagnostische beeldvormingstests moeten actief worden uitgevoerd om ischemische cerebrovasculaire gebeurtenissen uit te sluiten.

Het intracellulaire domein van CD40 is een krachtige Costimulatoire Ingredient in chimère  Antigen  Receptoren

De co-stimulerende domeinen die zijn ingebouwd in chimere antigeenreceptoren (CAR’s) van de tweede generatie en de derde generatie, hebben een sterke invloed op de functie van CAR-T-cellen . Hier hebben we CAR’s van de tweede generatie en de derde generatie onderzocht die het signaleringsdomein van de CD40-receptor herbergen als een nieuw costimulerend component in vergelijking met vergelijkbare CAR’s die het 4-1BB-domein dragen . In CAR’s van beide generaties was CD40 krachtiger dan 4-1BB bij het triggeren van de NF-KB-signaleringsroute.

In humane T-cellen van 2 donoren was CD40 vergelijkbaar met 4-1BB bij het opreguleren van co-stimulerende en activatiemarkers, het induceren van pro-inflammatoire cytokinesecretie en het mediëren van het doden van doelwitcellen. Interessant genoeg waren er duidelijk verschillen in het responspatroon van T-cellen van de 2 donoren met betrekking tot CD40 en 4-1BB. We concluderen dat in menselijke T-cellen het CD40- signaleringsdomein een krachtig co-stimulerend component is in CAR’s van zowel de tweede generatie als de derde generatie.

Een systematische herziening van de rol van chimere  Antigeen  Receptor  T (CAR-T) celtherapie bij de behandeling van solide tumoren

Chimere antigeenreceptor T (CAR-T) celtherapie maakt gebruik van de eigen T-lymfocyten van de patiënt die zijn ontworpen om kankercellen aan te vallen. Het is door de Meals and Drug Administration (FDA) goedgekeurd voor verschillende hematologische maligniteiten en wordt momenteel geëvalueerd bij solide kankers in vroege fase-onderzoeken. We deden een systematische assessment bestaande uit 15 prospectieve klinische onderzoeken (n = 159) die CAR-T-cellen in solide kankers evalueerden . Vroege fase-onderzoeken toonden veelbelovende responspercentages bij ovariumepitheelkanker (100%), humaan epidermale groeifactorreceptor  (HER2)-positief sarcoom (67%) , epidermale groeifactorreceptor (EGFR)-positieve galwegkanker (65%), gevorderde maag-/pancreaskanker (82%), hepatocellulair carcinoom (67%),en colorectale kanker (70%) .

De mediane algehele respons voor alle maligniteiten was 62% (bereik 17%-100%) . De mediane progressievrije overleving en de totale overleving werden in de meeste onderzoeken niet bereikt. Cytokine-afgiftesyndroom werd gezien bij slechts één patiënt met cholangiocarcinoom die EGFR-specifieke CAR-T-celtherapie kreeg. Hoewel de overlevingsgegevens nog steeds niet volgroeid zijn, liet CAR-T-celtherapie bij solide maligniteiten bemoedigende responspercentages zien en werd goed verdragen.

Verschillen in lymfoompatiënten tussen chimeer  antigeen  receptor  van T-cel therapeutische proeven en bevolking

Chimere antigeenreceptor (CAR)-T-celtherapieën lijken veelbelovende behandelingen te zijn voor non-Hodgkin- en B-cellymfoom. Verschillende CAR-T-therapieën die zijn goedgekeurd door de Amerikaanse Meals and Drug Administration, zijn echter alleen op werkzaamheid getest in relatief weinig klinische onderzoeken met een enkele arm met kleine steekproefomvang. We probeerden de verschillen tussen patiënten in deze onderzoeken en de algemene populatie van patiënten met non-Hodgkin- en B-cellymfoom te onderzoeken. Vijfhonderdtweeëntwintig patiënten uit 15 CAR-T-onderzoeken gevonden in een systematische assessment en 417.492 patiënten uit de Surveillance, Epidemiology, and Finish Outcomes (SEER) Program-database werden vergeleken.

De deelnemers aan de CAR-T-studie leken jonger (46,7% jonger dan 70 jaar vs. 42,2%) , meer mannelijk (68,0% vs. 55,7%) en werden gedurende een kortere periode gevolgd in vergelijking met patiënten in de SEER-populatie (gemiddelde [M] 45,6 maanden, 95% betrouwbaarheidsinterval [BI] 17,7 tot 63,three maanden follow-up vs. M 57,1 maanden, 95% BI 57,Zero tot 57,three maanden overleving). Deelnemers aan de CAR-T-studie kunnen aanzienlijk verschillen van de algemene populatie van patiënten met non-Hodgkin- en B-cellymfoom . De effectiviteit van CAR-T-therapieën bij de algemene populatie van lymfoompatiënten kan verschillen van de effectiviteit die is aangetoond in onderzoeken. Nieuw gecreëerde CAR-T-patiëntenregisters zijn essentieel om de effectiviteit van de therapieën op populatieniveau huge te stellen.

CMV Control lentiviral particles (Bsd)

CMV-Null-Bsd 1 x107 IFU/ml x 200ul
EUR 349
Description: Negative control lentivirus contains a null spacer insert under CMV promoter, serves as the negative control of lentivurs treatment for the specificity of any target expression effects. It also has the blasticidin marker under RSV promoter.

CMV Control lentiviral particles (Neo)

CMV-Null-Neo 1 x107 IFU/ml x 200ul
EUR 349
Description: Negative control lentivirus contains a null spacer insert under CMV promoter, serves as the negative control of lentivurs treatment for the specificity of any target expression effects. It also has the Neomycin marker under RSV promoter.

CMV Control lentiviral particles (Puro)

CMV-Null-Puro 1 x107 IFU/ml x 200ul
EUR 349
Description: Negative control lentivirus contains a null spacer insert under CMV promoter, serves as the negative control of lentivurs treatment for the specificity of any target expression effects. It also has the Puromycin marker under RSV promoter.

EBAG9 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV)

LV694975 1.0 ug DNA
EUR 514

CMV Control lentiviral particles (GFP-Bsd)

CMV-Null-GB 1 x107 IFU/ml x 200ul
EUR 349
Description: Negative control lentivirus contains a null spacer insert under CMV promoter, serves as the negative control of lentivurs treatment for the specificity of any target expression effects. It also has the GFP-Blasticidin fusion marker under RSV promoter.

CMV Control lentiviral particles (GFP-Puro)

CMV-Null-GP 1 x107 IFU/ml x 200ul
EUR 349
Description: Negative control lentivirus contains a null spacer insert under CMV promoter, serves as the negative control of lentivurs treatment for the specificity of any target expression effects. It also has the GFP-Puromycin fusion marker under RSV promoter.

CMV Control lentiviral particles (RFP-Bsd)

CMV-Null-RB 1 x107 IFU/ml x 200ul
EUR 349
Description: Negative control lentivirus contains a null spacer insert under CMV promoter, serves as the negative control of lentivurs treatment for the specificity of any target expression effects. It also has the RFP-Blasticidin fusion marker under RSV promoter.

CMV Control lentiviral particles (RFP-Puro)

CMV-Null-RP 1 x107 IFU/ml x 200ul
EUR 349
Description: Negative control lentivirus contains a null spacer insert under CMV promoter, serves as the negative control of lentivurs treatment for the specificity of any target expression effects. It also has the RFP-Puromycin fusion marker under RSV promoter.

CMV control lentivirus (Hygro)

CMV-Null-Hygro 1 x107 IFU/ml x 200ul
EUR 349
Description: Negative control lentivirus contains a null spacer insert under CMV promoter, serves as the negative control of lentivurs treatment for the specificity of any target expression effects. It has the hygromycin selection under RSV promoter.

CMV control lentivirus (Zeo)

CMV-Null-Zeo 1 x107 IFU/ml x 200ul
EUR 349
Description: Negative control lentivirus contains a null spacer insert under CMV promoter, serves as the negative control of lentivurs treatment for the specificity of any target expression effects. It has the Zeocin selection under RSV promoter.

EBAG9 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV-C-term-HA)

LV709564 1.0 ug DNA
EUR 316

EBAG9 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV-GFP-2A-Puro)

LV709565 1.0 ug DNA
EUR 374

EBAG9 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV-RFP-2A-Puro)

LV709566 1.0 ug DNA
EUR 374

EBAG9 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV-C-term-HA)

LV694976 1.0 ug DNA
EUR 514

EBAG9 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV-GFP-2A-Puro)

LV694977 1.0 ug DNA
EUR 572

EBAG9 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV-RFP-2A-Puro)

LV694978 1.0 ug DNA
EUR 572

CMV Control lentiviral particles (Bsd) in PBS

CMV-Null-Bsd-PBS 1 x108 IFU/ml x 200ul
EUR 710
Description: Negative control lentivirus contains a null spacer insert under CMV promoter, serves as the negative control of lentivurs treatment for the specificity of any target expression effects. It also has the blasticidin marker under RSV promoter. The virus was concentrated and provided in PBS solution.

CMV Control lentiviral particles (Neo) in PBS

CMV-Null-Neo-PBS 1 x108 IFU/ml x 200ul
EUR 710
Description: Negative control lentivirus contains a null spacer insert under CMV promoter, serves as the negative control of lentivurs treatment for the specificity of any target expression effects. It also has the Neomycin marker under RSV promoter. The virus was concentrated and provided in PBS solution.

CMV Control lentiviral particles (Puro) in PBS

CMV-Null-Puro-PBS 1 x108 IFU/ml x 200ul
EUR 710
Description: Negative control lentivirus contains a null spacer insert under CMV promoter, serves as the negative control of lentivurs treatment for the specificity of any target expression effects. It also has the Puromycin marker under RSV promoter. The virus was concentrated and provided in PBS solution.

CMV Control lentiviral particles (GFP-Bsd) in PBS

CMV-Null-GB-PBS 1 x108 IFU/ml x 200ul
EUR 710
Description: Negative control lentivirus contains a null spacer insert under CMV promoter, serves as the negative control of lentivurs treatment for the specificity of any target expression effects. It also has the GFP-Blasticidin fusion marker under RSV promoter. The virus was concentrated and provided in PBS solution.

CMV Control lentiviral particles (GFP-Puro) in PBS

CMV-Null-GP-PBS 1 x108 IFU/ml x 200ul
EUR 710
Description: Negative control lentivirus contains a null spacer insert under CMV promoter, serves as the negative control of lentivurs treatment for the specificity of any target expression effects. It also has the GFP-Puromycin fusion marker under RSV promoter. The virus was concentrated and provided in PBS solution.

CMV Control lentiviral particles (RFP-Bsd) in PBS

CMV-Null-RB-PBS 1 x108 IFU/ml x 200ul
EUR 710
Description: Negative control lentivirus contains a null spacer insert under CMV promoter, serves as the negative control of lentivurs treatment for the specificity of any target expression effects. It also has the RFP-Blasticidin fusion marker under RSV promoter. The virus was concentrated and provided in PBS solution.

CMV Control lentiviral particles (RFP-Puro) in PBS

CMV-Null-RP-PBS 1 x108 IFU/ml x 200ul
EUR 710
Description: Negative control lentivirus contains a null spacer insert under CMV promoter, serves as the negative control of lentivurs treatment for the specificity of any target expression effects. It also has the RFP-Puromycin fusion marker under RSV promoter. The virus was concentrated and provided in PBS solution.

EBAG9 Lentiviral Vector (Human) (UbC) (pLenti-GIII-UbC)

LV709567 1.0 ug DNA
EUR 316

EBAG9 Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV709568 1.0 ug DNA
EUR 316

DRD5P1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723353 1.0 ug DNA Ask for price

DRD5P2 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723359 1.0 ug DNA Ask for price

DSTNP1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723383 1.0 ug DNA Ask for price

DSTNP3 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723389 1.0 ug DNA Ask for price

DTX2P1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723395 1.0 ug DNA Ask for price

DURS1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723401 1.0 ug DNA Ask for price

DUSPP Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723407 1.0 ug DNA Ask for price

DUTP1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723413 1.0 ug DNA Ask for price

DUTP2 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723419 1.0 ug DNA Ask for price

DUTP4 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723425 1.0 ug DNA Ask for price

DUTP5 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723431 1.0 ug DNA Ask for price

DUTP6 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723437 1.0 ug DNA Ask for price

DUTP7 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723443 1.0 ug DNA Ask for price

DUTP8 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723449 1.0 ug DNA Ask for price

DUX4L8 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723455 1.0 ug DNA Ask for price

DUX4L10 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723461 1.0 ug DNA Ask for price

DUX4L11 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723467 1.0 ug DNA Ask for price

DUX4L14 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723473 1.0 ug DNA Ask for price

DUX4L16 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723479 1.0 ug DNA Ask for price

DUX4L17 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723485 1.0 ug DNA Ask for price

DUX4L18 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723491 1.0 ug DNA Ask for price

DUX4L19 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723497 1.0 ug DNA Ask for price

DUXB Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723503 1.0 ug DNA Ask for price

DVL1L1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723509 1.0 ug DNA Ask for price

DWS Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723515 1.0 ug DNA Ask for price

DYNLL1P2 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723521 1.0 ug DNA Ask for price

DYRK1AIP1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723527 1.0 ug DNA Ask for price

DYRK1AIP2 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723533 1.0 ug DNA Ask for price

DYT2 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723539 1.0 ug DNA Ask for price

DYT4 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723545 1.0 ug DNA Ask for price

DYT7 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723551 1.0 ug DNA Ask for price

DYT10 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723557 1.0 ug DNA Ask for price

DYT13 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723563 1.0 ug DNA Ask for price

DYT15 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723569 1.0 ug DNA Ask for price

DYT17 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723575 1.0 ug DNA Ask for price

DYT21 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723581 1.0 ug DNA Ask for price

DYT22 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723587 1.0 ug DNA Ask for price

DYX1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723593 1.0 ug DNA Ask for price

DYX2 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723605 1.0 ug DNA Ask for price

DYX3 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723611 1.0 ug DNA Ask for price

DYX4 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723617 1.0 ug DNA Ask for price

DYX5 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723623 1.0 ug DNA Ask for price

DYX6 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723629 1.0 ug DNA Ask for price

DYX7 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723635 1.0 ug DNA Ask for price

DYX8 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723641 1.0 ug DNA Ask for price

DYX9 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723647 1.0 ug DNA Ask for price

E2F3P2 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723659 1.0 ug DNA Ask for price

E2F4P1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723665 1.0 ug DNA Ask for price

E11S Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723671 1.0 ug DNA Ask for price

EBM Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723683 1.0 ug DNA Ask for price

EBR3 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723689 1.0 ug DNA Ask for price

EBR4 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723695 1.0 ug DNA Ask for price

EBVM1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723701 1.0 ug DNA Ask for price

EBVS1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723707 1.0 ug DNA Ask for price

ECA1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723713 1.0 ug DNA Ask for price

ECEL1P1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723719 1.0 ug DNA Ask for price

ECEL1P3 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723725 1.0 ug DNA Ask for price

EDDM3DP Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723731 1.0 ug DNA Ask for price

EEC1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723737 1.0 ug DNA Ask for price

EEC2 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723743 1.0 ug DNA Ask for price

EEF1A1P3 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723749 1.0 ug DNA Ask for price

EEF1A1P4 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723755 1.0 ug DNA Ask for price

EEF1A1P15 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723761 1.0 ug DNA Ask for price

EEF1A1P16 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723767 1.0 ug DNA Ask for price

EEF1A1P17 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723773 1.0 ug DNA Ask for price

EEF1A1P18 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723779 1.0 ug DNA Ask for price

EEF1A1P22 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723785 1.0 ug DNA Ask for price

EEF1A1P23 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723791 1.0 ug DNA Ask for price

EEF1A1P25 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723797 1.0 ug DNA Ask for price

EEF1A1P26 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723803 1.0 ug DNA Ask for price

EEF1A1P28 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723809 1.0 ug DNA Ask for price

EEF1A1P29 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723815 1.0 ug DNA Ask for price

EEF1A1P30 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723821 1.0 ug DNA Ask for price

EEF1A1P31 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723827 1.0 ug DNA Ask for price

EEF1A1P33 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723833 1.0 ug DNA Ask for price

EEF1A1P34 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723839 1.0 ug DNA Ask for price

EEF1A1P35 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723845 1.0 ug DNA Ask for price

EEF1A1P38 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723851 1.0 ug DNA Ask for price

EEF1A1P40 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723857 1.0 ug DNA Ask for price

EEF1A1P41 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723863 1.0 ug DNA Ask for price

EEF1A3 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723869 1.0 ug DNA Ask for price

EEF1B2P5 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723875 1.0 ug DNA Ask for price

EEF1DP1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723881 1.0 ug DNA Ask for price

EEF1DP4 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723887 1.0 ug DNA Ask for price

EEGV1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723893 1.0 ug DNA Ask for price

EGI Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723929 1.0 ug DNA Ask for price

EIF2AP1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723947 1.0 ug DNA Ask for price

EIF2AP2 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723953 1.0 ug DNA Ask for price

EIF2AP3 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723959 1.0 ug DNA Ask for price

EIF2AP4 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723965 1.0 ug DNA Ask for price

EIF2S2P1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723983 1.0 ug DNA Ask for price

EIF2S2P3 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723989 1.0 ug DNA Ask for price

EIF2S2P6 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723995 1.0 ug DNA Ask for price

EIF2S2P7 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV724001 1.0 ug DNA Ask for price

EIF3EP2 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV724007 1.0 ug DNA Ask for price

EIF3FP1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV724013 1.0 ug DNA Ask for price

EIF3FP2 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV724019 1.0 ug DNA Ask for price

EIF4A1P6 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV724025 1.0 ug DNA Ask for price

EIF4A1P9 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV724031 1.0 ug DNA Ask for price

EIF4A1P11 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV724037 1.0 ug DNA Ask for price

EIF4A2P1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV724043 1.0 ug DNA Ask for price

EIF4BP2 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV724049 1.0 ug DNA Ask for price

EIF4BP4 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV724055 1.0 ug DNA Ask for price

EIF4BP9 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV724061 1.0 ug DNA Ask for price

EIF4EBP1P Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV724067 1.0 ug DNA Ask for price

EIF4EP1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV724073 1.0 ug DNA Ask for price

EIF4EP2 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV724079 1.0 ug DNA Ask for price

EIF5AL3 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV724085 1.0 ug DNA Ask for price

EIF5AP2 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV724091 1.0 ug DNA Ask for price

EIF5AP3 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV724097 1.0 ug DNA Ask for price

EJM2 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV724103 1.0 ug DNA Ask for price

EKV3 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV724109 1.0 ug DNA Ask for price

ELK2AP Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV724115 1.0 ug DNA Ask for price

ELK2BP Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV724121 1.0 ug DNA Ask for price

ELL2P1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV724127 1.0 ug DNA Ask for price

ELL2P2 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV724133 1.0 ug DNA Ask for price

ELL2P4 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV724139 1.0 ug DNA Ask for price

ELMO2P1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV724151 1.0 ug DNA Ask for price

EMWX Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV724175 1.0 ug DNA Ask for price

ENO1P3 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV724193 1.0 ug DNA Ask for price

ENO1P4 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV724199 1.0 ug DNA Ask for price

ENSAP1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV724217 1.0 ug DNA Ask for price

ENSAP3 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV724223 1.0 ug DNA Ask for price

ENUR1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV724229 1.0 ug DNA Ask for price

ENUR2 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV724235 1.0 ug DNA Ask for price

ERCM1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV724253 1.0 ug DNA Ask for price

ERDA1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV724259 1.0 ug DNA Ask for price

ERHP1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV724265 1.0 ug DNA Ask for price

ERHP2 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV724271 1.0 ug DNA Ask for price

ERLEC1P1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV724283 1.0 ug DNA Ask for price

ERPL1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV724289 1.0 ug DNA Ask for price

ESA4 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV724661 1.0 ug DNA Ask for price

ESAT Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV724667 1.0 ug DNA Ask for price

ESB3 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV724673 1.0 ug DNA Ask for price

ETF1P2 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV724679 1.0 ug DNA Ask for price

ETF1P3 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV724685 1.0 ug DNA Ask for price

ETM1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV724691 1.0 ug DNA Ask for price

EVR3 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV724703 1.0 ug DNA Ask for price

EXOSC3P1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV724709 1.0 ug DNA Ask for price

EXOSC3P2 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV724715 1.0 ug DNA Ask for price

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